来源:必赢76net线路2020-08-28浏览次数:7624

吕镗烽

博士研究生导师简介

姓名

吕镗烽

研究方向:

胸部肿瘤学,急性肺损伤及ARDS,肺部重症感染

联系方式

手机:13952016932

E-mailbairoushui@163.com

学术兼职:

任中华医学会慢阻肺联盟委员,中华医学会呼吸分会肺癌学组委员,江苏省医学会和江苏省医师协会呼吸分会委员, CSCO临床数据专业委员会委员,中国肺癌防治联盟预防委员会委员,中国肺癌防治联盟青年委员会委员,江苏研究型医院学会肺结节与肺癌MDT专委会常委,江苏省康复医学会呼吸康复委员会委员,江苏省医学会呼吸分会肺癌学组秘书,肿瘤学年鉴(中文版)秘书,《Translational Lung Cancer Research》杂志副主编。

个人简介

必赢76net线路附属金陵医院呼吸与危重症医学科副主任,副主任医师,必赢76net线路博士生导师,南京医科大学和南方医科大学硕士生导师,美国德州理工大学访问学者,《Translational Lung Cancer Research》杂志副主编。

主持和承担国家自然科学基金、江苏省自然科学基金和江苏省社会发展项目等多项研究课题,可支配经费500余万元。以第一作者和通讯作者发表研究论文近百篇,其中SCI论文50余篇,主编主译专著2本。获得省部级科技奖励2次。

代表性论文[5年通讯作者和第一作者]

序号

论文名称

刊物名称及ISSN

发表年份---

本人

排名

1

WNT5B exerts oncogenic effects and is negatively regulated by miR-5587-3p in lung adenocarcinoma progression.

Oncogene.

2020 39(7):1484-1497

共同通讯

2

LncRNA GMDS-AS1 inhibits lung adenocarcinoma development by regulating miR-96-5p/CYLD signaling.

Cancer Med.

2020 9(3):1196-1208

共同通讯

3

Geranylgeranyl diphosphate synthase 1 knockout ameliorates ventilator-induced lung injury via regulation of TLR2/4-AP-1 signaling.

Free Radic Biol Med.

2020 147():159-166

共同通讯

4

The Diagnostic Yield of Closed Needle Pleural Biopsy in Exudative Pleural Effusion: A Retrospective 10-year Study.  

Ann Transl Med

2020 Apr;8(7):491.

通讯作者

5

Treatment with convalescent plasma for COVID-19 patients in Wuhan, China.

Med Virol.

2020 Apr 15:10.1002/jmv.25882. Online ahead of print.

通讯作者

6

Encephalitis as a clinical manifestation of COVID-19.

Brain Behav Immun.

2020 Apr 10:S0889-1591(20)30465-7. Online ahead of print.

通讯作者

7

Prolonged SARS-CoV-2 RNA shedding: Not a rare phenomenon.

Med Virol.

2020 Apr 29:10.1002/jmv.25952. Online ahead of print.

通讯作者

8

Zebrafish Xenograft Model of Human Lung Cancer for Evaluating Osimertinib Resistance.

Biomed Res Int.  

2314-6133

2019():3129748

共同通讯

9

 Treatment of uncommon mutations in non-small cell lung cancer: new evidence and treatment.

Transl Lung Cancer Res.

2218-6751

2019,8(3):302-316

共同通讯

10

Efficacy of rapid on-site evaluation for diagnosing pulmonarylesions and mediastinal lymph nodes: a systematic review andmeta-analysis

Transl Lung Cancer Res.  

2218-6751

2019,8(6):1029-1044

通讯作者

11

Downregulation of GSDMD attenuates tumor proliferation via the intrinsic mitochondrial apoptotic pathway and inhibition of EGFR/Akt signaling and predicts a good prognosis in non small cell lung cancer.

Oncol Rep.

1021-335X

2018,40(4):1971-1984.

共同通讯

12

Expression profiles and clinical value of plasma exosomal Tim-3 and Galectin-9 in non-small cell lung cancer.

Biochem Biophys Res Commun.

0006-291X

2018,498(3):409-415.

共同通讯

13

The correlation between crizotinib efficacy and molecular heterogeneity by next-generation sequencing in non-small cell lung cancer.   

J Thorac Dis.

2072-1439

2018,10(5):2948-2959.

第一作者

14

RNA sequencing enables systematic identification of platelet transcriptomic alterations in NSCLC patients.

Biomedicine & Pharmacotherapy.

0753-3322

2018,105 (2018) 204–214.

共同通讯

15

TEAD4 exerts pro-metastatic effects and is negatively regulated by miR6839-3p in lung adenocarcinoma progression.  

J Cell Mol Med.

1582-4934

2018,22(7):3560-3571.

共同通讯

16

Comparison of clinical and radiological characteristics between anaplastic lymphoma kinase rearrangement and epidermal growth factor receptor mutation in treatment naïve advanced lung adenocarcinoma

J Thorac Dis

2072-1439

2017,9(10):3927-3937

共同通讯

17

Patterns and functional implications of platelets upon tumor "education"

Int J Biochem Cell Biol

1357-2725

2017,90:68-80

共同通讯

18

Erlotinib-based doublet targeted therapy versus erlotinib alone in previously treated advanced non-small-cell lung cancer: a meta-analysis from 24 randomized controlled trials

Oncotarget

1949-2553

2017,8(42):73258-73270

共同通讯

19

Protein regulator of cytokinesis-1 expression: prognostic value in lung squamous cell carcinoma patients

J Thorac Dis

2072-1439

2017,9(7):2054-2060

共同通讯

20

PRC1 contributes to tumorigenesis of lung adenocarcinoma in association with the Wnt/β-catenin signaling pathway

Mol Cancer

1476-4598

2017,16(1):108

共同通讯

21

NCAPG2 promotes tumour proliferation by regulating G2/M phase and associates with poor prognosis in lung adenocarcinoma

J Cell Mol Med

1582-4934

2017,21(4):665-676

共同通讯

22

Long intergenic noncoding RNA 00673 promotes non-small-cell lung cancer metastasis by binding with EZH2 and causing epigenetic silencing of HOXA5

Oncotarget

1949-2553

2017,8(20):32696-32705

共同通讯

23

Detection of oncogenic mutations in resected bronchial margins by next-generation sequencing indicates early relapse in stage IA lung adenocarcinoma patients

Oncotarget

1949-2553

2017,8(25):40643-40653

共同一作

24

Long non-coding RNA 00312 regulated by HOXA5 inhibits tumour proliferation and promotes apoptosis in Non-small cell lung cancer

J Cell Mol Med

1582-4934

2017,21(9):2184-2198

共同一作

25

Pulmonary ground-glass opacity: computed tomography features, histopathology and molecular pathology.

Transl Lung Cancer Res.

2218-6751

2017,6(1):68-75.

共同通讯

26

Correlation in histological subtypes with high resolution computed tomography signatures of early stage lung adenocarcinoma.

Transl Lung Cancer Res.

2218-6751

2017,6(1):14-22.

共同通讯

27

Transthoracic needle aspiration in solitary pulmonary nodule.

Transl Lung Cancer Res.

2218-6751

2017,6(1):76-85.

共同通讯

28

How to diagnose pulmonary nodules: from screening to therapy.

Transl Lung Cancer Res.

2218-6751

2017,6(1):3-5.

共同通讯

29

The pulmonary nodule ""discovered"" by pneumonia: a case rep

Transl Lung Cancer Res.

2218-6751

2017,6(1):92-96.

共同通讯

30

Comparison between endobronchial ultrasound-guided transbronchial biopsy and CT-guided transthoracic lung biopsy for the diagnosis of peripheral lung cancer: a systematic review and meta-analysis.

Transl Lung Cancer Res.

2218-6751

2017,6(1):23-34.

共同通讯

31

The imaging of small pulmonary nodules.

Transl Lung Cancer Res. Transl Lung Cancer Res.

2218-6751

2017,6(1):62-67.

共同通讯

32

Circulating long noncoding RNA GAS5 is a novel biomarker for the diagnosis of non-small cell lung cancer

Medicine (Baltimore)

0025-7974

2016,95(37):e4608

共同一作

33

Upregulation of long intergenic noncoding RNA 00673 promotes tumor proliferation via LSD1 interaction and repression of NCALD in non-small-cell lung cancer

Oncotarget

1949-2553

2016,7(18):25558-75

共同通讯

34

The role of TWIST1 in epithelial-mesenchymal transition and cancers

Tumour Biol

1010-4283

2016,37(1):185-97

通讯作者

35

Twist1-mediated 4E-BP1 regulation through mTOR in non-small cell lung cancer

Oncotarget

1949-2553

2015,6(32):33006-18

共同一作


承担科研项目[项目负责人]

序号

项目名称

项目来源

项目起讫

时间

项目负责人

入账经费(万元)

1

CRISPR/Cas9调节的 PD-1体外敲除联合MUC1PSCA CAR-T技术治疗晚期非

江苏省科技厅社会发展--面上项目BE2019718

2019.07-

2022.06

吕镗烽

100

2

血小板外泌体来源的长非编码RNA Linc01021调控肺腺癌转移的机制研究

国家自然科学基金--面上项目

81772500

2018.01-

2021.12

吕镗烽

53

3

非编码RNAncRNA)在非小细胞肺癌早期诊断和预后中的研究

南京市国际联合研发项目

201715009

2017.07-

2020.06

吕镗烽

5

4

高表达的linc01021在女性肺腺癌发生发展中作用的研究

江苏省自然科学基金(BK20161386

2016.07-2019.07

吕镗烽

10

5

基于多组学技术支撑zPDX模型的晚期非小细胞肺癌精准诊疗新平台的建立及推广应用

江苏省科技厅

社会发展--重点项目-临床前沿技术(BE2019719

2019.07-

2022.06

吕镗烽(第二负责人)

400


获奖情况

获奖成果名称

获奖类型与等级

评奖单位

获奖

时间

本人排名

非小细胞肺癌精准诊治转化研究及临床应用

科技进步二等奖

教育部

2016

2