吴江
电话:邮箱:wujiang@nju.edu.cn 地址:研究方向:
环境污染与健康、生殖与发育 教育和工作简历: 2012年12月–至今,必赢76net线路,必赢76net线路,副教授,硕士生导师 2009年8月–2010年8月,美国University of California at Riverside, 访问学者 2009年9月获必赢76net线路内科学博士学位 教学: 先后承担《生理学》、《疾病研究的生物学方法》、《炎症与疾病》、《病原生物学》、《医学寄生虫学》、《生殖生物学》等多门本科/研究生课程;“十二五”普通高等教育本科国家级规划教材,科学出版社《生理学》第四版编委。 1 Xiaoyan Li, Xin Zhuang, Tianchi Xu, Min Mao, Cong Wang, Yabing Chen, Xiaodong Han*, Jiang Wu*. Expression analysis of microRNAs and mRNAs in ovarian granulosa cells after microcystin-LR exposure. Toxicon. 2017, 129:11-19. doi: 10.1016/j.toxicon.2017.01.022. 2 Jie Ding, Jing Wang, Haibo Jin, Tian Xia, Yi Cheng, Jiang Wu*, Xiaodong Han*. Microcystin-LR reduces the synthesis of gonadotropin-releasing hormone by activating multiple signaling pathways resulting in decrease of testosterone in mice. Science of the Total Environment. 2018, 643:496-506. doi: 10.1016/j.scitotenv.2018.06.123. 3 Ling Chen, Jiwei Hou, Xiao Fu, Xiang Chen, Jiang Wu*, Xiaodong Han*. tPA promotes the proliferation of lung fibroblasts and activates the Wnt/β-catenin signaling pathway in idiopathic pulmonary fibrosis. Cell Cycle. 2019 Nov;18(22):3137-3146. doi: 10.1080/15384101.2019.1669997. 4 Xiaoyan Li1, Jinling Zhu1, Jie Tian, Dongmei Li, Xiaodong Han*, Jiang Wu*. MC-LR induced overproduction of progesterone via inhibiting miR 5 Jinling Zhu1, Kunyang Liu1, Ligang Pei, Xinyue Hu, Yuchen Cai, Jie Ding, Dongmei Li, Xiaodong Han*, Jiang Wu*. The mechanisms of mitochondrial dysfunction and glucose intake decrease induced by Microcystin-LR in ovarian granulosa cells. Ecotoxicology and Environmental Safety. 2021 Apr 1;212:111931. doi: 10.1016/j.ecoenv.2021.111931. 6 Kunyang Liu1, Xiaonan Zhao1, Meihong Guo, Jinling Zhu, Dongmei Li, Jie Ding, Xiaodong Han*, Jiang Wu*. Microcystin-leucine arginine (MC-LR) induces mouse ovarian inflammation by promoting granulosa cells to produce inflammatory cytokine via activation of cGAS-STING signaling. Toxicol Lett. 2022 Jan 12;S0378-4274(22)00014-5. doi: 10.1016/j.toxlet.2022.01.003. 7 Meihong Guo1, Lei yang1, Xiaonan Zhao, Pinru Yan, Mengjiao Zhu, Weidong Ding, Dongmei Li, Xiaodong Han*, Jiang Wu*. Microcystin-LR inhibits early pregnancy by impairing the vascular network of luteum: Involvement of the MEK/ERK/SP1/VEGFR2 axis. Food Chem Toxicol. 2022 Oct 4;113454. doi: 10.1016/j.fct.2022.113454. 1、国家自然科学基金面上项目:微囊藻毒素-LR诱导雌性小鼠卵巢颗粒细胞凋亡、卵泡闭锁加速的机制研究(31670519) 2、国家自然科学基金青年项目:微囊藻毒素-LR长时期低剂量暴露对雌性小鼠生殖功能的影响及其机制研究(31200401)2019年必赢76net线路优秀教师 |